Kaposiform Hemangioendothelioma in a Newborn with Kasabach-Merritt Syndrome

نویسندگان

  • Maryam Kazemi Aghdam Pediatric Pathology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Roxana Azma Pediatric Radiology Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  • Shahnaz Armin Pediatric Infections Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
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Kaposiform hemangioendothelioma with distant lymphangiomatosis without an association to Kasabach-Merritt-Syndrome in a female adult!

Kaposiform hemangioendothelioma (KHE) is a locally aggressive vascular tumor which usually occurs in infants. Clinically it appears as ill-defined red to purple indurated plaque. KHE is commonly associated with Kasabach-Merritt syndrome (KMS) and lymphangiomatosis. Microscopically, the tumor is composed of infiltrating lobulated nodules with slitlike or crescentic vessels which are poorly canal...

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[Kaposiform haemangioendothelioma with Kasabach-Merritt phenomenon].

Kasabach-Merritt phenomenon is a serious coagulopathy associated with kaposiform hemangioendothelioma (KHE), tufted angioma, and possibly other vascular neoplasms. KHE presenting in the absence of Kasabach-Merritt phenomenon is rare, although tufted angioma frequently occurs without thrombocytopenia. We retrospectively reviewed 10 cases of KHE without Kasabach-Merritt phenomenon. The tumors app...

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Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon: successful treatment with embolization and vincristine in two newborns.

Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor and has a high mortality in newborns when associated with Kasabach-Merritt syndrome (KMS). In two newborns with KHE and severe KMS refractory to medical treatment, emergency embolization led to clinical improvement in the acute neonatal setting by reducing tumor volume, increasing the platelet count, and improving other clotting par...

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Sirolimus for treatment of kaposiform hemangioendothelioma associated with Kasabach-Merritt phenomenon

KHE: kaposiform hemangioendothelioma KMP: Kasabach-Merritt phenomenon INTRODUCTION Kaposiform hemangioendothelioma (KHE) was first described by Zuckerberg et al in 1992. KHE is defined as a rare, locally aggressive infiltrative vascular neoplasm that typically occurs during infancy and childhood. KHE generally originates on the skin as a distinctive cutaneous lesion with ill-defined borders, la...

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عنوان ژورنال

دوره 8  شماره None

صفحات  125- 126

تاریخ انتشار 2016-12

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